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Shaver, J
Three changes distinguish it from the native fragment: a lactam bridge between the Asp5 side-chain carboxyl and the Lys10 side-chain amine, inversion to D-phenylalanine at position 7, and norleucine in place of the oxidation-prone methionine at position 4
Because it is a non-peptide molecule, it doesnt require empty-stomach dosing
Scientists continue to explore all this peptide has to offer
Individuals have reported hair loss when taking these drugs, as well as aspiration (when food or liquid enters the airway) when sedated for surgery, likely due to the delay in stomach emptying caused by the drugs
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