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TATA and CAAT are absent in human CYP51A1 , but the 5-prime of intron 1 is enriched with ~64.7% GC and is contained in a CpG island [22]

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Lastly, fibulin 3 (FBLN3), an extracellular matrix protein, suppresses both EMT and self-renewal of the lung cancer stem cells by inhibiting the IGF-IR/PI3K/AKT/GSK3 pathway [77]

Acknowledgements We thank the core facilities of the Flow Cytometry Core, Metabolomics Core, and the Laboratory of Animal Research at the Convergence Medicine Research Center (CREDIT), Asan Medical Center, for the use of their shared equipment, services, and expertize