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En estudios metabolmicos se han descrito con frecuencia seales de disfuncin del metabolismo energtico , incluyendo cambios en lpidos y, en algunos casos, alteraciones en la fraccin de carnitina/acil-carnitinas
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Inhibitors Pieces of evidence for the transcriptional regulation of NRF2 highlighted that modifications of the NFE2L2 promoter region such as hypermethylation or single nucleotide polymorphisms, are responsible for a decreased NRF2 expression
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