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Similar content being viewed by others Background Drugs that inhibit dipeptidyl peptidase-4 (DPP-4) are conventionally regarded as incretin-based agents that enhance the actions of endogenous gastrointestinal hormones (glucose-like peptide-1 [GLP-1] and glucose-dependent insulinotropic polypeptide) to promote the release of insulin from the pancreas [1, 2]
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At the recent International Federation of Surgery for Obesity/ Metabolic Disease (IFSO Santiago 2025), there has been similar discussions about redefining clinical obesity to improve engagement with government bodies and expanding surgery coverage
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