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Step 6: Set clear stop criteria Establish specific triggers for discontinuing GLP-1 therapy

But the real-world data tells a different story smaller weight loss, higher costs, and uncertain long-term outcomes

A potential unique mechanism with GLP-1s is their impact on the brain in regards to dopamine reward pathways, says Dr Terri-Lynne South, a general practitioner specialising in obesity medicine

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In men it also produced a measurable increase in lean body mass compared with placebo, along with improved insulin sensitivity and general well-being