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Improper needle depth, inconsistent site selection, and poor reconstitution practices all introduce variables that the clinical trials controlled for
semaglutide users at 12 months post-index, 39.2% and 58.4% of cohort 1 received 0.5 mg and 1.0 mg, respectively
The efficacy of subcutaneous semaglutide was established in the phase III SUSTAIN program (SUSTAIN 15 and 7), in which significant reductions in mean glycated hemoglobin (HbA 1c ) and body weight were demonstrated against placebo and a variety of active comparators in multiple patient groups with T2D [26,27,28,29,30,31,32,33]
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