Once phosphorylated the tyrosine residues of the beta subunit serve as docking sites for downstream signaling mediators including extracellular signal-regulated kinase (ERK) and the phosphatidylinositol-3-kinase (P13K) pathway [75]
Tretter V, Jacob TC, Mukherjee J, Fritschy J-M, Pangalos MN, Moss SJ
Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms
The trials did not include DXA or MRI body composition analysis
Studies on GHK-Cu include topical skin research, diabetic wound-healing research, cell studies, animal models, and formulation studies [2], [3], [14], [15]