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As these pathways are important for Mtb virulence and to prevent the buildup of potentially toxic metabolites, it is vital to Mtb that these pathways are rigorously regulated

GEP44 is linked to high-energy expenditure, which takes the form of increased movement, heart rate or body temperature, says Doyle, Deans Professor of Chemistry in the College of Arts and Sciences

At the cellular level, it promotes collagen synthesis and fibroblast migration, supporting the structural repair of damaged gut tissue

GLP-1 and GIP receptor agonists have a low intrinsic risk of causing hypoglycaemia when used alone, because their insulin-stimulating effects are glucose-dependent

Mass spectrometry confirmation of the correct molecular weight is also important