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The result is a 16-amino acid peptide that stimulates lipolysis through beta-3 adrenergic receptors on fat cells, without triggering IGF-1 elevation, insulin resistance, or the growth-promoting effects that make full HGH problematic for long-term metabolic use

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The FDA and the EMA have stated that after review of published and unpublished reports, the current data do not support an increased risk of pancreatitis and pancreatic cancer in patients receiving incretin mimetics