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This established the mechanistic rationale for NNMT inhibition
2019. Altered NAD+ metabolism in metabolic disorders
Adult Dosing Dosage may vary based on different medical indications: For the initial treatment of vitamin B12 deficiency, the usual dose is 1000mcg SC/IM, given once a day for 1 week, followed by 1 dose a week for 1 month
Primary Research Areas NNMT enzymology and pharmacology the lead first-in-class selective small-molecule NNMT inhibitor used to validate the entire target class [1,2]
Adverse events were defined as a skin reaction at the site of injection, fever within 30 days of the vaccine, or enlarged or tender lymph nodes
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