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Islet amyloid polypeptide (IAPP) IAPP, a protein that is coexpressed and cosecreted with insulin by cells, forms membrane-permeable toxic oligomers and accumulates in the ER under continuous demand for insulin
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Science 307(5710):731734 Kumar P, Monin L, Castillo P, Elsegeiny W, Horne W, Eddens T et al (2016) Intestinal interleukin-17 receptor signaling mediates reciprocal control of the gut microbiota and autoimmune inflammation
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Research Overview Understanding Semaglutide Semaglutide is the second-generation long-acting GLP-1 analog developed by Novo Nordisk, building on the structural template established by liraglutide but engineered for substantially improved pharmacokinetics
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