For diabetes management, if HbA1c remains above target despite maximal tirzepatide dosing, combination therapy with metformin, SGLT2 inhibitors, or basal insulin should be considered based on individual patient factors and contraindications
Both drugs are GLP-1s, but Zepbounds active ingredient is tirzapetide and Wegovys is semaglutide
Bupleurum falcatum has been traditionally utilized as a medicinal herb in Korean medicine belonging to the Apiaceae family
Jason Giffi, DO, DABOM board-certified in obesity medicine, a certified personal trainer, and an Ironman triathlete
Clinical Trial Results: Weight Loss & Key Outcomes Phase 2 (Published in NEJM & Nature Medicine) Obesity trial (NEJM 2023): Up to 24.2% mean weight loss at 48 weeks (12 mg dose)