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NaOH) to unmask the free acid for downstream activation to NHS
the probe is also suited to metabolic glycoengineering and cell-based studies where membrane permeability is required prior to intracellular deprotection
/ CMP-N-acetylneuraminic acid / CMP-Neu5Ac
27 / A β-D-glucose ligand equipped with a terminal carboxylic acid through a short butyl spacer
/ 4-Nitrophenyl β-D-GlcNAc (Peracetate) / 4-Nitrophenyl 2-acetamido-3
AG642010: α-M6P-Butyl-Carboxylic Acid Pack Size:10 mg NaOH) to unmask the freeC11H21O11P 360. 25 An mannose 6 phosphate (Man6P) ligand equipped with a terminal carboxylic acid through a short butyl spacer. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on proteins and peptides to form stable amide bonds. This compound enables the construction of lysosome targeted therapeutics and research tools that exploit the mannose
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