Cuglievan B, Kantarjian H, Armstrong S, Rubnitz J, Zwaan M, Dinardo C, Cooper T, Pollard J, Kadia T, Guest E, Short N, McCall D, Daver N, Nunez C, Haddad F, Garcia M, Bhalla K, Maiti A, Catueno S, Fiskus W, Gibson A, Roth M, Khazal S, Tewari P, Abbas H, Bourgeois W, Andreeff M , Gruber T, Shukla N, Truong D, Connors J, Joseph Ludwig J, Stutterheim J, Salzer E, Dam KJ, Sasaki K, Mahadeo K, Tasian S, Borthakur G, Dickson S, Faulk K, Jain N, Jabbour E, Meshinchi S, Garcia Manero G, Ravandi F, Stein E, Kolb A, Issa G
Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses
Lactic acid is an anti-wrinkle and pigmentation fighting ingredient while kojic acid improves the appearance of fine lines, pores, and wrinkles improving skin elasticity
These metabolites may significantly contribute to ACs in vivo efficacy, supporting the view that AC acts as a prodrug whose therapeutic effects are mediated, at least in part, through its microbial transformation products
And many people buy it as a "research chemical" and use it themselves