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They are used primarily in the treatment of type 2 diabetes and obesity
Reported concerns include local injection reactions, potential immunogenicity from copper exposure with chronic use, and theoretical risks if peptides activate unintended growth pathways
Some people maintain their tirzepatide supply temporarily in case the switch to semaglutide does not go smoothly and they need to revert
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While recognizing their effectiveness in addressing obesity, many employers indicated they were considering scaling back coverage
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