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Specifically, three are a total of 7 newly formed interfacial salt bridges (Table 7) which are due to the four site-specific missense mutations L23B R, I20B Q, V24B R and R25B A

Possible side effects may include nausea, vomiting, diarrhea, constipation, abdominal discomfort, appetite changes, or other symptoms

The National Academies Guide for the Care and Use of Laboratory Animals provides widely used principles for animal research oversight and care

Animals Adult wild-type male C57BL/6 N mice were purchased from Orient Bio (Sungnam, South Korea)