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For example, a 2016 study highlighted how high doses of Vitamin B12, alongside other B vitamins, helped reduce pain and improve nerve conduction in diabetic patients

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Collagen remodeling takes time (a fibroblast doesn't build new collagen overnight), so this is the window where visible skin firmness, texture, and hair density improvements become most noticeable

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Some people are unable to manufacture Intrinsic Factor, a condition called pernicious anemia, making it impossible to absorb Vitamin B12 from foods or oral supplements