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additional contraceptive methods are recommended for 4 weeks after initiation and after each dose increase [3] [6] Tirzepatide is not recommended in patients with severe gastrointestinal disease, including severe gastroparesis Patients should inform all healthcare providers, including surgical teams, about tirzepatide use Treatment is likely long-term, as weight regain typically occurs upon discontinuation Patients should be monitored for adequate nutrition and hydration, particularly if appetite suppression is pronounced

Tirzepatide weight loss programs in Philadelphia, PA Tirzepatide is the only approved dual GLP-1 and GIP receptor agonist producing the highest average weight loss of any non-surgical medication currently available

STEP-1 lasted 68 weeks, SURMOUNT-1 lasted 72 weeks, and TRIUMPH-4 lasted 68 weeks, but the latter was conducted on a specific population (obesity with knee osteoarthritis)

Last updated: July 2, 2026 What Is Tirzepatide

The program integrates the medication with dietary guidance and a movement plan appropriate to your current fitness level