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In my experience, patients taking injectable semaglutide typically lose more weight than those on oral semaglutide, says Craig Primack, MD , a physician specializing in obesity medicine and senior vice president of weight management at Hims & Hers
Those medications target both GLP-1 and another gut hormone, GIP
Understanding your genetic context alongside biomarker data and clinical response empowers more precise provider dialogue about maintenance strategy, potential need for dose adjustments, and whether combination approaches or lower-dose protocols might optimize efficacy and tolerability for your unique biology
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Studies have found that many people regain weight after stopping weight loss injections, as renewed hunger and cravings drive them to increase their calorie intake
