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Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis
Moreover, whether the exosomes continuously secreted by the engineered cells, as a delivery vector themselves, will transfer the genetic modification effects laterally to distant tissue cells and thereby cause toxicity, is also an urgent issue that needs to be deeply clarified as a safety concern [168]
However, researchers have compared the impact of both drugs from different studies (this is called an indirect analysis) and suggested that the higher doses (10mg and 15mg) of tirzepatide might reduce HbA1c by 0.36% more than 2mg of semaglutide
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Steinert JR, Chernova T, Forsythe ID
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