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Moreover, with the maximum oral dosage plasma levels are lower compared with the maximal subcutaneous dose (oral 20 mg yields plasma levels of ~25 nM, subcutaneous 1 mg yields plasma levels of ~45 nM ( Table 2 )

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Oral options are also being developed to simplify administration and are long-awaited by those patients who are reluctant to use injections.Long-term use and patient expectations GLP-1 therapy should be considered a long-term treatment

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It also stresses that persistent or severe symptoms should be evaluated by a provider rather than assumed to be the medication at work