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186188 It has also been reported that the effects of liraglutide on decreasing the hyperphosphorylation of tau by enhancing O-glycosylation of neuronal cytoskeleton protein, improving the JNK and ERK signaling pathway

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dose adjustments of concomitant medications may be necessary Renal function : Dehydration from gastrointestinal side effects may precipitate acute kidney injury, particularly in patients with pre-existing renal impairment

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This distinction is particularly useful in experimental designs where separation of adipose-specific signaling from systemic endocrine effects is required