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For blood glucose measurements one drop of blood from the tail vein was collected and analysed using a handheld blood glucose meter (Accu-Chek Aviva)
5 Conclusion In summary, GLP-1RAs have revolutionized obesity and diabetes management, offering potent weight loss and cardiometabolic benefits, but are best used in conjunction with lifestyle interventions, particularly exercise, to optimize health outcomes and sustainability
However, several clinical studies have shown that GLP-1 intervention did not improve hepatic steatosis in NAFLD patients 18,19
Because they are supplements rather than prescription medications, systemic side effects are less defined, but the lack of clinical testing means overall safety remains uncertain
Tirzepatide (Zepbound) Clinical trial data cited by multiple sources, including NBC News, showed average weight loss of approximately 21 to 22.5 percent at the highest dose after 72 weeks, compared with about 3 percent for placebo
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