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Irisin, for example, enhances thermogenesis by promoting expression of brown-fat-related genes, which expend more energy than ordinary fat

The G-protein beta and gamma subunits (G) subunits downstream of G-protein-coupled receptors (GPCRs), also trigger activation of p110

Zuogui-Jiangtang-Yishen decoction prevents diabetic kidney disease: Intervene pyroptosis induced by trimethylamine n-oxide through the mROS-NLRP3 axis

206,347 In another study, treatment of primary mouse chondrocytes with liraglutide reduced the mRNA expression levels of iNOS, MMP-13, and ADAMTS5, leading to a decrease in the secretion of inflammatory markers, including NO, prostaglandin E, and IL-6

Presented for research literature review only Huynh K (2025)