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Brain and blood metabolome for Alzheimers dementia: findings from a targeted metabolomics analysis

In humans, the biotin-requiring enzymes include acetyl-CoA carboxylase (ACC: humans express two distinct ACC genes), pyruvate carboxylase (PC), propionyl-CoA carboxylase (PCC), and 3-methylcrotonyl-CoA carboxylase (3MCC)

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Its efficacy is demonstrated through the reduction of liver fat, improvement of liver function markers, and regulation of specific genes such as Atf3 and Acox2, supporting its development as a targeted therapy (82)

Talaat NB, Abdel-Salam SaM (2024) An innovative, sustainable, and environmentally friendly approach for wheat drought tolerance using vermicompost and effective microorganisms: upregulating the antioxidant defense machinery, glyoxalase system, and osmotic regulatory substances