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How GLP Drugs Work GLP-1 receptor agonists function by binding to the GLP-1 receptors on pancreatic beta cells, stimulating insulin release

Pharmacological alternatives that have evidence for binge eating disorder include: Lisdexamfetamine : Licensed in some countries specifically for moderate-to-severe BED in adults, though it is not licensed for this indication in the UK and is not recommended by NICE for BED

Figure 3 3.3.2 Efficacy of GLP-1 RAs on liver enzymes in MASLD Twenty reviews of the 24 meta-analyses examined the efficacy of GLP-1 RAs on liver enzymes, including ALT, AST, GGT, and ALP (Supplementary Table S6)

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