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They can cause these problems that we've been discussing
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It can not only indicate the occurrence and progression of diseases but also mediate interorgan crosstalk
FoB persist in the follicles in a quiescent state as they recirculate until activated by recognition of the antigen by their B cell receptors and the T cell-mediated cognate help, whereupon they proliferate and undergo germinal center (GC) reactions 6,17
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