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Notably, derivatives bearing L-sugar configurations outperformed their D-sugar counterparts, for instance, 3-O-(2,3,4-tri-O-acetyl--L-glucopyranosyl)-caudatin (Figure 1g) exhibited the highest activity against HepG2 cells (IC 50 3.11 M) (Li X
Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance
The lower dose needed to achieve comparable blood levels means less unabsorbed berberine irritating the digestive tract
GBA1-Associated Parkinsons disease is a distinct entity
However, these effects are usually mild and tend to improve over time
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