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99 B12 deficiency in infants can cause anaemia, abnormal skin and hair development, convulsions, failure to thrive, mental developmental delay and possibly abnormal movements, and direct supplementation of the infant is recommended in such cases

A common community model uses 300 mcg per day for four weeks, followed by 500 mcg per day for the rest of an 8- to 16-week timeline

Patients using injectable protocols (250-500 mcg daily) reported symptom improvements within 2-3 weeks, while those using oral formulations (500-1000 mcg daily) required 4-6 weeks for comparable benefits