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M., Dudziec, E., Peter, S., Bertz, S., Hartmann, A., Bryant, H
DSIP is found in both free and protein-bound forms in the hypothalamus, limbic system, and pituitary gland, as well as in peripheral organs including the gut secretory cells, pancreas (where it co-localises with glucagon), and plasma with brain and plasma DSIP concentrations showing a marked diurnal variation that correlates with circadian rhythm in humans, with levels lowest in the morning and higher in the afternoon
Competitive oxidation of key pentose phosphate pathway enzymes modulates the fate of intermediates and NAPDH production
For oral vs injectable route evidence, see BPC-157 Oral vs Injectable
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