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Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants

Some people may experience mild digestive upset when they first start a supplement, but this often resolves quickly

Here we present the antioxidant GSH as a potential unexplored way for further investigation as intervention to counteract inflammaging, premature inflammaging, inflammatory diseases and long-COVID-19-syndrome, since GSH levels are correlated with tissue and organ damage, disease severity and progression, and disease outcome (294296, 298, 299)

Pyruvate can be transported into the matrix, where PDH will convert it to Acetyl-CoA