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Caspase-9 is activated in a cytochrome C-independent manner early during tnf-induced apoptosis in murine cells
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mTOR inhibitor, rapamycin, has been shown to increase radiation-induced DNA damage 33
Indeed, progressive RT (15 climbs, progression from 15%75% of MCL over 4 weeks) performed on alternating days attenuated neuroinflammation in the frontal cortex and hippocampus of mice by reducing mRNA expression of TNF- and protein concentrations of IL-1 (Liu et al., 2020)
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