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PubMed, Wegovy OKd for Teens With Obesity
It was also somewhat reassuring to see that heart failure rates were lower with SGLT2 inhibitors, as one would expect, he said, because these agents have been shown to significantly reduce the risk of hospitalization for heart failure in multiple outcome trials, whereas GLP-1 receptor agonists beneficial CV effects appear to be more limited to MACE reduction. The higher rates of discontinuation with GLP-1 receptor agonists is also not a surprise, since patients experience more gastrointestinal tolerability issues with these agents (mainly nausea), which can be mitigated in the majority of patients with appropriate education and close follow up but is not done consistently
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GLP-1 Injections are prescription medications used to support weight management and metabolic health
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