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The improvement in lipid metabolism and immune function was further confirmed in companion publications by the same research group, which showed connections between global DNA methylation and its effect on proliferator-activated receptor alpha (PPAR) (Osorio et al., 2016)
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Body Composition: Ensuring that weight loss is coming from adipose tissue
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Either people really have to accept this as a treatment for life,, or we in science need to think really, really hard, how to support people when they stop the drug. While the study did not show causality, Jebb speculated that the difference in how fast people put weight back on could be due to the fact that diets are hard and people have to practise restraint to lose weight, whereas if you are taking a drug that knocks your hunger out completely, you dont have to make that effort
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