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In one published case, an active, lean-adjacent man lost about one-third of his total weight as muscle on 2.5 mg and recovered it after adding resistance training and increasing protein. This is a cautionary case, not an incidence estimate
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In this week's Smart Medicine Evidence Substack Update, I break down: What the committee actually recommended Why this matters What physicians and patients need to know today Why the sciencenot the headlinesshould guide clinical decisions The link to my latest Smart Medicine Substack is in the first comment
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