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Therefore, drugs that are metabolized by CYP3A4 may be metabolized quicker, leading to decreased plasma concentrations and potential therapeutic failure

Myosteatosis alters muscle fiber composition and organization, with a decrease in oxidative, insulin-sensitive fibers and a concomitant increase in relatively fast-fatiguing glycolytic fibers, paralleling the effects observed in obesity and aging

Dutta P, Kumar Y, Babu AT, Giri Ravindran S, Salam A, Rai B, et al

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