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When healthy cells generate energy (adenosine triphosphate, or ATP) through the mitochondrial electron transport chain, they naturally produce highly reactive oxygen species (ROS) as a metabolic byproduct
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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
In addition, the enzyme did not tolerate photoreduction in the presence of EDTA ( Results SmTGR C159S reductive half-reaction Published X-ray crystal structures of SmTGR reveal what appears to be a chain of three cysteine pairs which could act as electron carriers to move electrons derived from NADPH to specific parts of the enzyme to reduce oxidant substrates (Figure 1
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