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"Efficacy and safety of oral orforglipron in patients with type 2 diabetes: a multicentre, randomised, dose-response, phase 2 study"
These individual unimolecular multi-agonists activities seemed to harmonize the overall metabolic efficacy, which predominantly results from synergistic glucagon action to increase energy expenditure, GLP-1 action to reduce caloric intake and improve glucose control, and GIP action to potentiate the incretin effect and buffer against the diabetogenic effect of inherent glucagon activity
Targets pulsatile growth hormone release
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The Wegovy pill should not be taken alongside Wegovy injection, Mounjaro or another GLP-1 medicine
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