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Lastly, IRI advances into regional cell necrosis, apoptosis, and autophagy resulting in neuron loss, specially RGCs (159)

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Lumps lasting over 2 hours usually result from injecting too rapidly (under 10 seconds for 1 mL), injecting into scar tissue with poor blood flow, or using a formulation with precipitates

Due to this enzymatic reaction, a variety of glucosinolate hydrolysis products (GHPs) can be generated such as isothiocyanates (ITCs), nitriles, epithionitriles and thiocyanates depending on the GSL substrate and reaction conditions 3

One notable advantage of our assay is that it enables accurate measurements of GPx activity, even when working with low substrate concentrations