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GLP-1 has been studied extensively in type 2 diabetes as a novel insulinotropic peptide whose actions are predicated upon the ambient glucose concentration
It is synthesized from three amino acids: glutamate, cysteine, and glycine
Accordingly, we encourage the adoption of GLP-1RA plus SGLT2i combination therapy in patients with T2DM and established atherosclerotic cardiovascular disease (ASCVD) or multiple risk factors for ASCVD (i.e., age 55 years, overweight/obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria)
This may not sound like a big deal but it is
The current study differs from the study by Wong et al
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