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The deletion of NF-B signalling in microglia rescued motor neurons from microglia-mediated death and prolonged neuronal survival in ALS mice by preventing pro-inflammatory microglial activation ( Neurons and other post-mitotic cells are particularly vulnerable to DNA damage, which results in cell death if left untreated
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If you have one of those conditions, getting B12 injections can prevent a deficiency before it starts
It is standard medical advice to avoid non-essential supplements during these periods
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