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Studies have found that GLP-1R is widely distributed on pancreatic and other tissues and has multiple biological effects, such as reducing neuroinflammation, promoting nerve growth, improving heart function, suppressing appetite, delaying gastric emptying, regulating blood lipid metabolism, and reducing fat deposition
Gut-derived immune activation exacerbates central pathology in stroke and in autoimmune diseases like MS, while there is evidence that dietary interventions and probiotics can also attenuate disease severity and improve functional outcome
doi:10.1016/j.japh.2020.06.023 48
