GLP-1 stimulates insulin secretion in response to rising blood glucose, suppresses the opposing hormone glucagon, slows the rate at which the stomach empties, and reduces appetite by acting on satiety centres in the brain
Semaglutide has years of post-marketing surveillance data from millions of users
Results demonstrated: Up to 1.71% HbA1C reduction with 40 mg zenagamtide Statistically significant HbA1C improvement across all dose levels 89.1% of participants achieved HbA1C below 7% 76.2% achieved HbA1C at or below 6.5% Up to 91.4% time-in-range (70180 mg/dL) These findings suggest robust glucose-lowering efficacy despite limited exposure to the highest maintenance doses
You should also not take semaglutide if you are pregnant and, if youre taking it post-delivery, its recommended you should not breastfeed
Morelli MP, Overman M, Vilar E, Morris V, Fogelman D, Shureiqi I, Garret C, Kanwal R, Eng C, Kee B, Manuel S, Wolff R, Sebisanovic D, Sew L, Zapanta A, Shiller B, Mei G, Eltoukhy H, Talasaz AA, Kopetz S