Its a fascinating observation especially since these agents were never designed for T1DM
An expert on the special also taught Winfrey a metaphor that helped her better understand how obesity is a disease that makes people gain weight and requires medical treatment something she struggled with until she started taking a weight-loss medication
However, anecdotal reports from online forums cited in a 2025 systematic review included anxiety and panic attacks, depression and anhedonia, insomnia, heart palpitations, fatigue and weakness, and loss of appetite
It demonstrates excellent results in the long run, especially when combined with a balanced diet, proper exercise program, healthy lifestyle habits, and other crucial factors that directly influence ones quality of life
Before menopause: Estrogen directs fat storage primarily to hips and thighs During and after menopause: Lower estrogen shifts fat storage to the abdominal area, with visceral fat increasing from 5%-8% to 15%-20% of total body fat Why it matters: Belly fat (visceral fat) surrounds internal organs and is linked to increased risk of heart disease and type 2 diabetes Visceral fat differs from subcutaneous fat, which sits just under the skin