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Greater impact of combination therapy was seen among participants with higher levels of systemic inflammation at screening, which is known to drive joint disease activity and structural damage, suggesting that future studies should focus on this patient population.
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Tirzepatide causes gastrointestinal symptoms including nausea, vomiting, diarrhea, and constipation in a substantial percentage of users, particularly during dose escalation phases
In preclinical research dating back to the 1990s, BPC-157 has demonstrated remarkable effects across multiple body systems
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