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The net effect of Akt activation is a shift toward anabolism: more protein synthesis and less protein breakdown

Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson DA, et al

Although often perceived as a means of enhancing muscle mass and physical performance, this practice represents a growing public-health concern due to its wide-ranging endocrine, reproductive, and multisystem adverse effects

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Kumar M, Bansal N (2022) Implications of phosphoinositide 3-kinase-akt (PI3K-Akt) pathway in the pathogenesis of Alzheimers disease