En ACHIEVE-2, realizado en pacientes con diabetes tipo 2, quienes recibieron la dosis ms alta perdieron en promedio 8.9 kilogramos o 9.2% de su peso corporal durante 52 semanas , segn Lilly
Based on the guidelines for Good Epidemiological Practice and Good Practice in Secondary Data Analysis, no approval of an ethics committee was required for the secondary analysis [12]
The team, led by senior author Dr Ziyad Al-Aly of Washington University in St Louis, mapped the association between GLP-1RAs and 175 different health outcomes, using data from a total of over 2 million people obtained from the US Department of Veterans Affairs
Adverse Events and Treatment Discontinuation With GLP-1s, side effects are a common and expected consideration and can influence whether patients remain on treatment
While these studies show promising results, they often lack the rigor and relevance required to extrapolate findings to human subjects