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its acquisition and use outside research contexts carry legal and safety considerations

Among the 14 trials included, four excluded patients with heart failure, while the remaining nine articles excluded patients with heart failure, cardiac events (e.g., myocardial infarction, unstable angina, revascularization procedure, stroke) or cardiovascular diseases ( Supplementary Table 4 )

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It is believed to promote weight loss by increasing the bodys ability to burn fat, particularly during exercise