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Deletion of leptin receptors in vagal afferent neurons disrupts estrogen signaling, body weight, food intake and hormonal controls of feeding in female mice (140)
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Patients carrying certain alleles experience more rapid shifts in food preference, while others show a more gradual adjustment period
Nat Chem Biol 21 , 256267 (2025)
In adults without diabetes, a 72 mg dose of semaglutide led to an average weight loss of nearly 19%, surpassing the 16% loss seen with 24 mg and 4% with placebo
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