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Advanced / Aggressive Protocol (1 mL = ~10.0 mg/mL) Note: The 12 mg dose represents the highest dose tested in Phase 2 trials [3] [4] , producing maximum weight-loss efficacy (~24% body weight at 48 weeks)

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enhances skeletal muscle glucose uptake (Solomon et al., 2013) Metformin : activates AMPK , reduces hepatic glucose output

Lung Lesions and Anti-Ulcer Agents Beneficial Effect: Anti-Ulcer Agents Pentadecapeptide BPC 157, Ranitidine, Omeprazole and Atropine Ameliorate Lung Lesion in Rats